The Laboratory Rat. Biology and Diseases by Henry J. Baker, J. Russell Lindsey, Steven H. Weisbroth,

By Henry J. Baker, J. Russell Lindsey, Steven H. Weisbroth, Steven H. Wesibroth

The Laboratory Rat, quantity I: Biology and illnesses makes a speciality of using rats in particular components of study, starting from dental study to toxicology.
The first a part of this ebook retraces the biomedical background of early occasions and personalities all for the institution of rats as a number one laboratory animal. The taxonomy, genetics and inbred lines of rats also are elaborated. the subsequent chapters illustrate the hematology, scientific biochemistry, and anatomical and physiological positive aspects of the laboratory rat. this article concludes with an outline of infectious ailments that could be shrunk from laboratory and/or wild rats.
This quantity is an effective resource for advertisement and institutional firms all for generating rats for learn use, experts in laboratory animal, animal care and study technicians, in addition to scholars in graduate curricula.

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No doubt many others also originated in part or exclusively from commercial Wistars. Regardless, the Wistar bloodline has contributed far more strains of rats than any other single line. In fact, the contribution of the commer­ cial Wistar colony to the total gene pool of all modern strains and stocks of rats may exceed the combined influence of all other bloodlines! McCollum (101) purchased a stock of albino rats from a Chicago dealer in 1907, and subsequently introduced into his V Commercial Stock (s) Wild Norways Phila.

Castle, W. E. (1947). The domestication of the rat. Proc. Nati. Acad. Sci. A. 33, 109-117. Castle, W. E. (1951). Variation in the hooded pattern of rats and a new allele of hooded. Genetics 36, 254-266. Castle, W. , and Phillips, J. C. (1914). Piebald rats and selection. Carnegie Inst. Washington Pubi. 195. Chase, H. , chairman (1975). "NIH Rodent Repository," Report of the Committee on Maintenance of Genetic Stocks. Inst. Lab. Anim. C. Chittenden, R. H. (1938). "Biographical Memoir of Lafayette Be­ nedict Mendel, 1872-1935," Biogr.

1953). Attempts to isolate the active agent in Cysticercus fasciolaris. Cancer Res. 13, 838-843. Dunning, W. , and Curtis, M. R. (1957). A transplantable acute leukemia in an inbred line of rats. J. Nati. Cancer Inst. 19, 845-852. Dunning, W. , Curtis, M. , and Madsen, M. E. (1951). Diethylstilbestrol induced mammary gland and bladder cancer in reciprocal Fj hybrids between two inbred lines of rats. Acta Unio Int. Cancrum 7, 238-244. Eakin, R. M. (1956). History of zoology at the University of Califor­ nia, Berkeley.

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