8th Int'l Conference on Numerical Methods in Fluid Dynamics by Krause E. (ed.)

By Krause E. (ed.)

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The concentrations of the regulatory proteins ASF/SF2, SC35, and hnRNP A1 are denoted by ASF , SC35 , hnRNPA1 , respectively. Finally, η, η are kinetic constants. The A4 and A5 acceptor sites are not well-studied yet, due to the complexity of the corresponding nucleic acid domain [9]. Their local behaviour is captured by the splice efficiencies eff 4 and eff 5 , which are defined as interval constants. To model the relative interaction between those sites, we use default reasoning. Following [10], we describe A5 as a preferential activated site in the presence of regulatory proteins, and A4 as the default splicing site.

Q ] −→ β(x : {a}) [ P {v/u} ] β(y : {b}) [ Q ] with P(a, b) > 0. Namely, as it is shown above, instead of the classical unlabelled reduction relation, we could define a probabilistic relation. 1]. 4 Reverse Engineering Unknown Activation Processes Biology researchers are often puzzled by a number of events which they can observe to occur without having a clear understanding of the activation pathways leading to them. Our framework could be helpful in the investigation of those biological events.

The relative tendency of a solute object to move forward within a SS determines the effective flow pressure and this is governed by a parameter called Turbo. If there is no flow pressure (Turbo = 0), then solute movement is specified by a simple random walk. Increasing Turbo biases the random walk in the direction of the CV. We have studied the behaviors of several sinusoidal segment designs and describe here the extensible design currently in use. Simpler designs generate behaviors that fail to meet our Similarity Measure criterion.

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